October 8, 2024
Technology

Exploring Biomarker Technology to Enhance the Diagnosis and Treatment of PTSD in Justice-Involved Veterans


35 These are the hippocampus, amygdala, dorsomedial prefrontal cortex, and ventromedial prefrontal cortex. See: Ganzel, B. L., Kim, P., Glover, G. H., & Temple, E. (2008). Resilience after 9/11: Multimodal neuroimaging evidence for stress-related change in the healthy adult brain. Neuroimage, 40(2), 788-795. https://doi.org/10.1016/j.neuroimage.2007.12.010; Li, L., Wu, M., Liao, Y., Ouyang, L., Du, M., Lei, D., Chen, L., Yao, L., Huang, X., & Gong, Q. (2014). Grey matter reduction associated with posttraumatic stress disorder and traumatic stress. Neuroscience & Biobehavioral Reviews, 2014(43), 163-172. https://doi.org/10.1016/j.neubiorev.2014.04.003; Logue, M. W., van Rooij, S. J., Dennis, E. L., Davis, S. L., Hayes, J. P., Stevens, J. S., Densmore, M., Haswell, C. C., Ipser, J., & Koch, S. B. (2018). Smaller hippocampal volume in posttraumatic stress disorder: A multisite ENIGMA-PGC study: Subcortical volumetry results from posttraumatic stress disorder consortia. Biological Psychiatry, 83(3), 244-253. https://doi.org/10.1016/j.biopsych.2017.09.006; Rauch, S. L., Shin, L. M., Segal, E., Pitman, R. K., Carson, M. A., McMullin, K., Whalen, P., & Makris, N. (2003). Selectively reduced regional cortical volumes in post-traumatic stress disorder. Neuroreport, 14(7), 913-916. https://doi.org/10.1097/01.wnr.0000071767.24455.10; Rogers, M. A., Yamasue, H., Abe, O., Yamada, H., Ohtani, T., Iwanami, A., Aoki, S., Kato, N., & Kasai, K. (2009). Smaller amygdala volume and reduced anterior cingulate gray matter density associated with history of post-traumatic stress disorder. Psychiatry Research: Neuroimaging, 174(3), 210-216. https://doi.org/10.1016/j.pscychresns.2009.06.001; Wrocklage, K. M., Averill, L. A., Scott, J. C., Averill, C. L., Schweinsburg, B., Trejo, M., Roy, A., Weisser, V., Kelly, C., Martini, B., Harpaz-Rotem, I., Southwick, S. M., Krystal, J. H., & Abdallah, C. G. (2017). Cortical thickness reduction in combat exposed US veterans with and without PTSD. European Neuropsychopharmacology, 27(5), 515-525. https://doi.org/10.1016/j.euroneuro.2017.02.010



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